Preheat your oven to 350°F.

In a large bowl, combine the ground beef, eggs, and heavy cream. Mix thoroughly with your hands until well combined.

In a separate small bowl, whisk together the pork panko, Italian seasoning (if using), and salt.

Add the dry ingredients to the wet mixture and use your hands to mix everything evenly.

Transfer the meat mixture to a 9x5-inch loaf pan, smoothing the top for an even shape.

Bake the meatloaf for 75 minutes, or until it’s fully cooked and the internal temperature in the center reads 160°F.

Let the meatloaf rest for 10 minutes before slicing and serving.