Hearty, and endlessly customizable, this meatloaf is the definition of comfort food. With a few easy tricks, it turns out moist and flavorful every time. Make it healthier by using lean meats and sneaking in veggies, or go keto with low-carb swaps like almond flour and sugar-free ketchup. Whether served with mashed potatoes or tucked into sandwiches the next day, this timeless favorite keeps everyone coming back for seconds.
Preheat oven to 350°F (175°C). Lightly grease a 9x5-inch loaf pan or line a baking sheet with foil.
In a large bowl, combine the ground beef, onion, eggs, milk, breadcrumbs, garlic, 1/4 cup ketchup, parsley, Worcestershire sauce, salt, pepper and Italian seasoning. Mix until well combined, but do not overmix.
Shape the mixture into a loaf and place in the prepared pan or on the baking sheet.
In a small bowl, mix together the glaze ingredients. Brush half of the glaze evenly over the meatloaf.
Bake for 45 minutes, then brush with the remaining glaze. Continue baking for another 15-30 minutes, until the internal temperature reaches 160°F (71°C).
Let the meatloaf rest for 10-15 minutes before slicing and serving. Enjoy!